Probiotics Capsule Manufacturer for Global Brands

EUPHM operates encapsulation suites with controlled temperature (18–22°C) and relative humidity below 35% to protect probiotic viability. We run automatic capsule fillers for powder, pellet and beadlet formats, with fill weights from 200 mg to 800 mg. Changeover between SKUs is documented, and line clearance records are available for audit. Typical output is up to 1.2 million capsules per day across two shifts.

For brands scaling from pilot to retail, we hold MOQ at 1,000 units per SKU for standard bottle formats. Pilot runs below that threshold are possible with manual or semi-automatic filling. We can also produce blister packs, stick packs and sachets if your dosage form requires it. Capsule shell options include HPMC, gelatin, pullulan and enteric-coated HPMC for delayed release.

Probiotic strains vary in sensitivity to heat, moisture and oxygen. Our formulation team reviews your strain list and CFU targets before quoting. We blend with cryoprotectants such as trehalose or skim milk powder when needed, and we can add prebiotics like inulin or FOS. Overages are calculated to meet label claim at end of shelf life, not just at release. Typical overage ranges from 10% to 50% depending on strain and stability data.

We work with single-strain and multi-strain blends up to 10 strains per capsule. CFU targets range from 1 billion to 50 billion per capsule. For multi-strain products, we verify strain identity via third-party PCR testing where requested. Excipients such as magnesium stearate, silicon dioxide and microcrystalline cellulose are available, or we can formulate without them for clean-label positioning.

Every batch of probiotics capsules is tested for viable count, moisture content, and microbiological safety including total aerobic count, yeast and mould, E. coli, Salmonella and Staphylococcus aureus. We retain samples for the shelf life of the product. Stability studies follow ICH guidelines, with accelerated conditions at 40°C/75% RH and real-time conditions at 25°C/60% RH. Certificates of analysis are issued per batch.

Our facility is GMP-certified and registered with the relevant Chinese authorities. We hold ISO 22000 and HACCP certifications. For halal requirements, we source capsule shells and excipients from approved suppliers with valid certificates. Vegan and vegetarian capsule options are available. Documentation for EU and US import, including health certificates and free sale certificates, can be arranged.

Probiotics capsules are packed in HDPE bottles with induction seals and child-resistant closures where required, in blister packs with aluminium foil backing, or in single-serve stick sachets for powder formats. Bottle sizes range from 30 to 120 capsules, with desiccant canisters or silica gel sachets added to control headspace moisture. For stick packs, we run vertical form-fill-seal lines with nitrogen flushing to displace oxygen. Blister options include PVC/PVDC and alu-alu for moisture-sensitive strains. Cartons are printed to customer artwork with lot number and expiry date applied by inkjet or laser coding at packing.

Labels for the US market must include the statement of identity, net quantity of contents, supplement facts panel, ingredient list, allergen statement where applicable, and the manufacturer or distributor name and address. We support customers in checking that the supplement facts panel matches the formula and that the CFU claim is stated at end of shelf life where the brand chooses that convention. For EU markets, labels follow Regulation (EU) No 1169/2011 and the nutrition and health claims regulation, with the responsible person address included. We do not provide regulatory advice but will format artwork to the customer's approved text.

Lot and expiry coding is applied to each bottle, blister or sachet, and to the outer carton. Cartons are specified with a standard E-flute or B-flute corrugated board, with pallet configurations of 48 to 60 cartons per layer and up to five layers per pallet, stretch-wrapped and corner-boarded. For Amazon sellers, we can apply FNSKU labels and poly-bag units to Amazon's packaging requirements, and we can print suffocation warnings where required. Retail-ready shelf trays and display cartons are available on request.

Before mass production, we issue a packaging specification sheet showing bottle dimensions, cap type, desiccant quantity, label dimensions and carton weight. A pre-production sample is sent for customer approval, and the approved sample is retained as the packing standard. Any change to bottle supplier, desiccant or closure triggers a re-approval. Shipping cartons are drop-tested to ISTA 1A or 3A on request so that brands can assess whether retail packaging survives parcel networks.

Sampling starts with a formulation brief and a target strain list. Stock formulas can be sampled in 7 to 10 working days, while custom blends with new strain combinations take 10 to 15 working days because of potency verification and stability set-up. Samples are sent by courier with a preliminary COA and a packaging options sheet. Sample costs are credited against the first mass-production order where the order exceeds the MOQ.

Mass production runs 20 to 35 working days after sample approval and receipt of deposit, depending on capsule fill, packaging format and whether desiccant or nitrogen flushing is specified. Line capacity is up to 1.2 million capsules per day, but probiotics scheduling allows for cleaning and environmental monitoring between strains. Bottling and labelling add 3 to 5 working days to the capsule production window. We confirm a production slot in writing once artwork and purchase order are approved.

Shipments are quoted EXW, FOB Shenzhen or Hong Kong, or DDP to the customer's door. Air freight is typical for samples and launch quantities, with transit of 5 to 8 days to major hubs. Sea freight is used for full-container orders, with transit of 18 to 30 days depending on destination port. For probiotics, we recommend insulated or temperature-controlled options where the destination climate is hot, and we can provide gel packs or thermal liners on request. Shipping documents include commercial invoice, packing list, bill of lading or airway bill, COA, MSDS where applicable, and a free-sale certificate. A certificate of origin can be issued for preferential tariff treatment.

We do not ship probiotics capsules without a signed approval of the pre-production sample and a confirmed label proof. Where a customer needs a phytosanitary certificate or a halal certificate for a specific lot, we arrange this before shipment and include it in the document pack. Delivery terms, inspection rights and payment milestones are set out in the proforma invoice so that both parties have a clear record before production begins.