Vitamin B12 Liquid Manufacturer for Private Label Brands

Vitamin B12 Liquid Manufacturer for Private Label Brands

EUPHM fills vitamin B12 liquids in 15 ml, 30 ml and 60 ml bottles with droppers or spray pumps. MOQ starts at 1,000 units per SKU. Samples ship in 7–10 working days.

Overview

Liquid vitamin B12 suits sublingual and dropper formats where tablets are hard to swallow. We formulate methylcobalamin, cyanocobalamin or adenosylcobalamin at 500 mcg to 5,000 mcg per serving, in water, glycerin or alcohol-free bases. Flavours include natural berry, citrus and unflavoured. Bottling runs on a 30,000-unit daily line with in-line fill weight checks. Certifications cover GMP, ISO 22000, HACCP, plus halal and vegan where specified.

Key specifications
MOQ
1,000 units per SKU (pilot runs from 1,000)
Fill weights
15 ml, 30 ml, 60 ml; 10–60 ml custom
Sample lead time
7–10 working days
Mass production
20–35 working days after approval
Bottle formats
Dropper, spray pump, tamper-evident cap
Certifications
GMP, ISO 9001, ISO 22000, HACCP, NSF/ANSI 455-2, halal, FDA-registered
Operator at a filling line in the Guangzhou plant

Liquid B12 Filling Capacity and Formats

Liquid filling lines run at 30,000 bottles per day across 15 ml, 30 ml and 60 ml amber glass and PET. Each line carries inline fill weight verification to ±1.5%, with reject stations for underfill and cap torque faults. Dropper assemblies, spray pumps and tamper-evident closures are stocked for standard 18 mm and 20 mm necks. Changeover between SKUs takes 4–6 hours, which keeps multi-SKU orders practical for brands launching two or three strengths at once.

Bulk liquid B12 concentrate is held in stainless steel vessels under nitrogen to limit oxidation. Batches are filtered at 0.45 micron before filling. For brands scaling from a 1,000-unit pilot to 5,000-unit retail runs, the same equipment and QC parameters apply, so formulation and fill weight stay consistent between the pilot and the commercial batch. Lead time for mass production is 20–35 working days from approved sample and purchase order.

Formulation: Methylcobalamin, Cyanocobalamin and Blends

Vitamin B12 is stable in liquid when the base and pH are controlled. We formulate at pH 4.5–6.5 for methylcobalamin and 4.0–5.5 for cyanocobalamin, using glycerin, purified water or a glycerin-water blend. Alcohol-free and sugar-free bases are available. Typical actives range from 500 mcg to 5,000 mcg per 1 ml serving. We can combine B12 with B6, folate, biotin or electrolytes in one dropper or spray format without compromising clarity.

Flavour systems are matched to the active. Methylcobalamin carries a natural cherry or berry note well; cyanocobalamin is neutral and suits unflavoured or lightly sweetened bases. Stevia, monk fruit and erythritol are used at 0.2–0.8% to keep taste clean without adding sugar. Preservative systems include potassium sorbate and sodium benzoate at standard beverage levels, or a preservative-free hot-fill option for brands targeting clean-label claims.

Quality Control and Export Documentation

Each batch is tested for assay, pH, microbial limits, heavy metals and fill weight before release. Certificates of analysis are issued per lot. Stability testing runs at 25°C/60% RH and 40°C/75% RH for 6 and 12 months, with accelerated data available for retail submissions. The facility is GMP-certified and holds ISO 22000 and HACCP. Halal and vegan certification can be arranged where the formula and capsule or bottle components meet the relevant standard.

Export documentation covers commercial invoice, packing list, certificate of origin, health certificate and, where required, halal certificates. We ship FOB Shenzhen or Yantian, with air freight for pilot runs. Typical retail carton configuration is 24 or 48 bottles per shipper. EU, UK and US labelling support includes ingredient declarations, allergen statements and supplement facts panel formatting.

Quality Control and Batch Documentation

Every batch of liquid vitamin B12 undergoes identity testing by HPLC to confirm the correct cobalamin form and potency within a 95.0–105.0% label claim range. Microbial testing covers total aerobic count, yeast and mould, E. coli and Salmonella, with results available within 72 hours. Heavy metals (lead, arsenic, cadmium, mercury) are screened against EU and US pharmacopoeial limits. For liquids, we also test pH, viscosity and fill weight at start, middle and end of the filling run.

A Certificate of Analysis (COA) is issued per batch and includes batch number, manufacture and expiry dates, specification results, and a signed release statement. Retention samples of each batch are kept for two years at controlled temperature. Stability protocols follow ICH guidelines: 25°C/60% RH for 24 months, with accelerated testing at 40°C/75% RH for six months. Real-time data is available on request for ongoing projects.

Disintegration testing does not apply to liquids, but we verify homogeneity and absence of sedimentation after 30 days of storage. Preservative efficacy testing (PET) is performed if the formulation contains preservatives, using the ISO 11930 method. All testing is conducted in-house or at accredited third-party laboratories, and raw material COAs are retained for traceability. Documentation packages can be tailored to your market's regulatory requirements.

Packaging, Labelling and Retail Readiness

We offer dropper bottles in amber or clear glass, 15 ml, 30 ml and 60 ml, with tamper-evident droppers and child-resistant caps. Spray pumps are available for 20 ml and 30 ml formats. For single-serve convenience, stick packs and sachets from 5 ml to 10 ml can be produced on separate lines. Cartons are printed with lot number and expiry date using inkjet or laser coding, and each carton carries a linear barcode (UPC or EAN) as required.

For the US market, labels include the FDA dietary supplement facts panel, ingredient list, allergen statement, and 'Keep out of reach of children' warning. We can pre-press labels to your artwork, or design basic layouts if needed. For Amazon FNSKU labelling, we apply the FNSKU barcode over the original barcode or on the carton as specified. Retail-ready packaging options include shelf-ready trays and shrink-wrap for club stores.

Pallet specifications are built to your retailer's requirements: standard 1200x1000 mm or 1200x800 mm pallets, with maximum height 1.8 m, and stretch-wrapped and corner-protected. We provide packaging specifications and dielines for your approval before production. If you supply your own bottles or labels, we can accommodate customer-supplied components after a compatibility check.

MOQ, Lead Times and Delivery

The standard MOQ is 1,000 units per SKU for market testing. Sample lead time is 7–10 working days after receipt of your formulation brief and any custom artwork. Mass production takes 20–35 working days after sample approval and receipt of deposit. These timelines assume standard bottle and label components; custom tooling or imported components may add 2–3 weeks.

We ship via air freight for urgent orders (5–10 days door-to-door) or sea freight for larger volumes (25–40 days depending on destination). Incoterms offered include EXW, FOB Shenzhen or Hong Kong, and DDP for select countries. Shipping documents provided include commercial invoice, packing list, bill of lading or airway bill, COA, MSDS, and a free-sale certificate. For some destinations, a phytosanitary certificate or certificate of origin can be arranged.

Order progress is tracked through a shared production schedule, with photo updates at key milestones: raw material receipt, filling, labelling and packing. We recommend booking sea freight at least two weeks before production completion to avoid delays. For repeat orders, we keep your formulation and artwork on file, reducing lead time by 3–5 days.

Configurations to Compare

Methylcobalamin drops

500–5,000 mcg per 1 ml in a 30 ml dropper bottle. Natural berry or unflavoured. Suits sublingual positioning and vegan labels.

Cyanocobalamin spray

1,000–2,500 mcg per spray in a 15 ml or 30 ml pump. Neutral taste, alcohol-free base, 60–120 metered doses per bottle.

B12 + B-Complex liquid

B12 with B6, folate and biotin in one 30 ml dropper. Single daily serve. Useful for energy and nerve-support ranges.

B12 + electrolyte drops

B12 with sodium, potassium and magnesium in a 60 ml bottle. Light citrus flavour. Positioned for hydration and active-lifestyle lines.

From Spec to Shipment

  1. 01

    Share your brief

    Send target strength, bottle size, flavour direction, certifications and estimated first order quantity. We confirm feasibility within 2 working days.

  2. 02

    Receive a quote

    You get unit pricing, MOQ, tooling or mould costs if a custom bottle is needed, and a production timeline. No obligation at this stage.

  3. 03

    Approve samples

    We produce a lab sample or pilot batch in 7–10 working days. You review taste, fill weight and label fit before committing to a run.

  4. 04

    Confirm formulation

    Final specification is locked, including assay method, pH range, preservative system and stability protocol. You sign off the master batch record.

  5. 05

    Production and QC

    Mass production runs 20–35 working days. In-process checks cover fill weight, cap torque, microbial limits and assay. Certificates of analysis follow each lot.

  6. 06

    Ship and restock

    We pack to your carton configuration and ship FOB Shenzhen or Yantian. Reorders use the same master batch record for consistency.

Why EUPHM

Low MOQ for testing

Start at 1,000 units per SKU, with pilot runs from 1,000. Enough to validate a listing without tying up capital in a 10,000-unit first order.

Stable liquid formats

pH-controlled bases and nitrogen-blanketed bulk storage protect B12 potency through a 12-month shelf life. Stability data supports retail submissions.

Certifications that clear customs

GMP, ISO 9001, ISO 22000, HACCP, NSF/ANSI 455-2 and halal certification; FDA facility registration for US-bound shipments.

Questions buyers ask.

What is the MOQ for liquid vitamin B12?+

MOQ is 1,000 units per SKU for standard 15 ml, 30 ml and 60 ml bottles. Pilot runs start at 1,000 units. If you need a custom bottle mould, tooling adds cost and 15–20 working days to the timeline. Lower MOQs are possible for lab samples and market-test batches.

How long does a B12 liquid order take?+

Samples ship in 7–10 working days from brief approval. Mass production runs 20–35 working days after you approve the sample and issue a purchase order. Add 3–5 working days for third-party testing if your market requires it. Air freight from Shenzhen takes 3–7 days.

Can you make a vegan and halal B12 liquid?+

Yes. Methylcobalamin and cyanocobalamin are both suitable for vegan formulas. We use plant-derived glycerin and no animal-derived carriers. Halal certification can be arranged where the full formula, bottle and closure meet the standard. Certificates are issued per batch.

Which B12 form is more stable in liquid?+

Cyanocobalamin is the more stable form in aqueous and glycerin bases, with a typical 24-month shelf life. Methylcobalamin is stable when pH is held at 4.5–6.5 and the bulk is nitrogen-blanketed. We run stability testing at 25°C/60% RH and 40°C/75% RH to confirm the shelf life on your specific formula.

Do you provide stability and COA documents?+

Yes. Each production lot gets a certificate of analysis covering assay, pH, microbial limits, heavy metals and fill weight. Real-time and accelerated stability data are available for retail submissions. We can also work with your nominated third-party lab if your market requires an independent test report.

Can you supply vitamin B12 liquid in bulk or concentrate form?+

Yes, we can supply concentrated liquid B12 in 1 L or 5 L food-grade containers for further dilution or repackaging. However, bulk concentrate is only available for customers with their own filling facilities and quality control. We provide a COA and MSDS for each bulk lot, and can adjust concentration to your specification. Minimum order for bulk is 10 L.

What is the shelf life of your liquid vitamin B12 products?+

Shelf life is typically 24 months from date of manufacture when stored below 25°C and away from direct sunlight. We support this with real-time stability data and can provide accelerated stability results. If your formulation requires a shorter or longer shelf life, we can adjust the preservative system or packaging to suit. Expiry dates are printed on each unit and carton.

Do you offer low-volume or trial orders for new brands?+

Yes, we offer 1,000 units per SKU to help new brands test the market. Pilot orders use the same production line and quality standards as larger runs, but may incur a higher per-unit cost. We can also provide unlabelled samples for your own testing. Contact us with your target volume and we will confirm feasibility and pricing.

Have a product in mind?

Send us the brief and we will come back with a formulation direction, indicative price and a realistic lead time — usually within one working day.